Guides

What the human record holds, compound by compound

By the Decadewise team Education only Last reviewed 27 July 2026 19 pages in the section

This is the section where each compound gets one page, and the page opens with the same question rather than the same promise: what does the published human record contain for this molecule, and what does it not contain. Nineteen pages sit here, tiered by how much evidence exists rather than by what anyone hopes the compound does.

Short answer

What this section is: nineteen pages that each take one compound or one comparison, report what named trials and approved labels state about it, and stop where the record stops.

How it is tiered: three compounds carry large registrational programs with published figures, two carry a thin early human record, four have been studied almost entirely in animals, and one is a blend that has never been tested as a blend.

What sits alongside the compounds: the bacteriostatic water pages, the route and injection-site pages, and the head-to-head comparisons, because nearly every guide runs into all three.

What none of them do: pick an amount for a reader. Numbers appear as what a named trial tested or what an approved label prints, and nothing here turns that into a suggestion.

On this page

Why are these tiered by evidence instead of by goal?

Because the shape of an honest answer changes depending on whether a human trial exists at all, and a goal-based grouping hides exactly that difference behind an outcome word.

The split it produces: tirzepatide, semaglutide and tesamorelin come with phase 3 programs, published endpoints and approved labels. BPC-157, TB-500, MOTS-c and GHK-Cu do not have a completed randomized human trial between them on the form people buy.

Why that ordering matters: a page grouped under fat loss or recovery reads as though the four compounds under it are four options for the same job. Grouped by evidence, the first thing visible is that one of them has 72-week outcome data and another has rodents.

What does every guide in here have in common?

The same four moves, in the same order: what the molecule is, what named trials tested and reported, the arithmetic that joins a milligram figure on a label to a reading on a barrel, and an explicit statement of what the record does not cover.

Figures keep their conditions: a result is reported with its arm, its timepoint and its population attached, and figures from separate trials are never set side by side as though one experiment produced both.

An empty record is reported as empty: where no human trial exists, the guide says so and leaves the gap visible rather than filling it with a number that circulates online without an origin.

Where do the water, route, and comparison pages fit?

They are the shared dependencies. Almost every compound page runs into the same three questions underneath the compound itself: which water a vial is mixed with, which route a label names, and how the molecule differs from whatever it is sold beside.

Rather than repeating that nineteen times: each of those lives on its own page, gets sourced once, and is linked from the guides that need it. The bacteriostatic water pages carry the label definitions, the administration pages carry what approved labels specify about route, site and needle, and the comparison pages handle the pairs people keep merging.

The arithmetic lives elsewhere too: the conversions themselves are worked in the dose math section and run in the tools, so a guide can point at them instead of re-deriving the same division.

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The nineteen pages

Grouped by how much human evidence exists: the tier label on each card is the honest headline of the page behind it, not a rating of the compound.

Rich human data

Tirzepatide

SURMOUNT-1 tested three once-weekly amounts over 72 weeks. The guide sets those trial figures beside the vial arithmetic they get quoted with.

Read the guide

Rich human data

Semaglutide

STEP 1 ran one maintenance level over 68 weeks behind a staged escalation, with the approved pen strengths printed next to it.

Read the guide

Rich human data

Tesamorelin

Two phase 3 trials, a daily rhythm rather than a weekly one, and one narrow approved indication.

Read the guide

Limited human data

CJC-1295

A small early human record dosed by bodyweight, a development program that stopped, and the two versions forum posts keep merging.

Read the guide

Limited human data

Ipamorelin

Three published human studies, all old: a pharmacokinetics study, a phase 2 trial for postoperative ileus, and an intranasal study.

Read the guide

Research only

BPC-157

No completed randomized human trial, a large rodent record measured per kilogram, and thirty analyzed subjects across three uncontrolled pilots.

Read the guide

Research only

TB-500

Every human figure in the record belongs to the parent molecule, thymosin beta-4, and not to the seven-amino-acid fragment sold under the name.

Read the guide

Research only

MOTS-c

A mitochondrial peptide with a 2015 discovery paper, one completed trial of an analog, and a phase 2 trial recruiting with nothing public on its schedule.

Read the guide

Research only

GHK-Cu

The human record here is topical: a cream ulcer trial and post-laser skin care. The injectable lane has no human trial behind it at all.

Read the guide

Blend decode

KLOW

A four-compound blend with zero published studies on the blend itself. The guide decodes the components and reconciles the two reconstitution camps.

Read the guide

Water

What is bacteriostatic water

The label definition, how much benzyl alcohol each presentation carries, and the single indication the label states for it.

Read the explainer

Comparison

Bacteriostatic vs sterile water

One is water for injection with a preservative added, the other has nothing added. What the preservative buys is a multiple-dose container.

Read the comparison

Comparison

Bacteriostatic water vs saline

Saline is salt water at the concentration of blood and bacteriostatic water carries no solute, so the two differ on tonicity first.

Read the comparison

Label record

Subcutaneous vs intramuscular

An approved label names one route for its own product and rules the others out. What the metabolic and depot labels each specify.

Read the explainer

Trial record

Injection sites in the trials

The body regions the registered protocols allowed, and how a registry entry carries forward into the approved label.

Read the explainer

Label record

Needle gauges and syringe sizes

Gauge is a tubing size standardized in ISO 9626 and the number runs backwards. What the pen, vial and depot labels name for their own products.

Read the explainer

Comparison

HGH vs peptides

Somatropin is a 191-amino-acid chain identical to the pituitary hormone. The shorter sequences it gets compared to act one step upstream of it.

Read the comparison

Comparison

SARMs vs peptides

Nonsteroidal small molecules that bind the androgen receptor, against chains of amino acids: two chemical classes sharing one marketplace.

Read the comparison

Comparison

Tirzepatide vs semaglutide

SURPASS-2 put both in one protocol, one population and the same forty weeks, then reported every arm. What a single head-to-head cannot settle.

Read the comparison

The disclaimer

Every page is reviewed by medical professionals before it ships, and written with longtime biohackers who were doing this before it was a trend. Reviewed still does not mean prescribed: nothing here is medical advice. It is research, trial data, and reported use, with the numbers intact so you can check them. For decisions about your body, see a doctor who can look at your labs.

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