Classification
Is MK-677 a SARM
Ibutamoren is a growth hormone secretagogue acting at the ghrelin receptor, not a SARM, and it does not bind the androgen receptor.
Read the explainerClassification
Four pages sit here, and each one exists because a single label is being asked to answer three separate questions at once. What a molecule binds, what a statute defines, and what an anti-doping list prohibits are three different registers with three different authorities behind them, and a compound can land differently in each. These pages pull them apart and name the document behind every answer.
Short answer
What this section is: four pages that separate the questions people keep merging: what a molecule binds, what a statute covers, and what an agency prohibits.
Why the answers come apart: a compound can sit outside a legal definition and still be prohibited in sport, and it can be an unapproved drug while also being excluded from the supplement category. None of those answers implies the others.
What each page settles: MK-677 against the SARM label, ostarine against the statutory definition of an anabolic steroid, cardarine against both plus its carcinogenicity record, and bremelanotide against the one indication its approval covers.
What none of them are: legal advice, or a status check for any particular place. They report what named regulators and named agencies have published, with the document linked so it can be read directly.
Because the label travels as a shopping category rather than as a claim about a receptor, and a compound sold beside SARMs gets filed with them regardless of what it binds.
The worked example: MK-677, also called ibutamoren, agonizes the ghrelin receptor and prompts the pituitary to release more growth hormone. It never touches the androgen receptor, which is the receptor the term SARM is defined around.
Why the correction matters: the receptor determines what the compound does, what shows up on a test, and which regulatory documents apply to it. Getting the class wrong makes every downstream answer wrong too.
Receptor pharmacology: what the molecule binds and what happens when it does. This is settled in the published literature, and it is the only one of the three that is the same everywhere.
Statutory and regulatory status: whether a legal definition covers the molecule, and how an agency has filed it. A compound can fall outside the anabolic steroid definition and still be an unapproved new drug excluded from the supplement category.
Anti-doping status: whether an agency has listed it as prohibited, and in which class. That listing follows its own logic and does not wait for an approval or a schedule.
One product, one indication, and the population the trials enrolled. An approval is narrow by construction, and reading it as a general endorsement of the molecule is where most of the confusion starts.
The worked example: bremelanotide is approved as one product for one narrow indication, and the label carries a Limitations of Use section that states in writing which populations and uses the approval does not extend to.
The general rule: what a label excludes is as load-bearing as what it includes, and it is printed in the same document. The exclusions are quoted on each page rather than summarised away.
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Each one names its documents: the trial record, the statutory text, the agency filing, or the approved label, linked so the wording can be checked directly.
Classification
Ibutamoren is a growth hormone secretagogue acting at the ghrelin receptor, not a SARM, and it does not bind the androgen receptor.
Read the explainerClassification
Enobosarm binds the receptor testosterone binds without being built on a steroid backbone. What the federal definition covers, and where FDA has filed it instead.
Read the explainerClassification
A PPAR-delta agonist with no androgen receptor activity, the discovery programme it came out of, and why development was terminated.
Read the explainerApproval record
One approved product covering one narrow indication, and a Limitations of Use section that states in writing what the approval excludes.
Read the explainerEvery page is reviewed by medical professionals before it ships, and written with longtime biohackers who were doing this before it was a trend. Reviewed still does not mean prescribed: nothing here is medical advice. It is research, trial data, and reported use, with the numbers intact so you can check them. For decisions about your body, see a doctor who can look at your labs.
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